化学
转移加氢
串联
甲酸
双功能
催化作用
酒
环境友好型
组合化学
配体(生物化学)
铱
有机化学
转化(遗传学)
钌
受体
复合材料
材料科学
基因
生物
生物化学
生态学
作者
Lu Ouyang,Renshi Luo,Nianhua Luo,Yuhong Zhong,Jitian Liu
出处
期刊:Synthesis
[Thieme Medical Publishers (Germany)]
日期:2020-08-11
卷期号:52 (22): 3439-3445
被引量:8
标识
DOI:10.1055/s-0040-1707233
摘要
A practical and efficient method for the synthesis of alcohols in one pot from readily available alkynes via a tandem process by formic acid promoted hydration and metal-ligand bifunctional iridium-catalyzed transfer hydrogenation under mild conditions has been described. This transformation is simple, efficient, and can be performed with a variety of alkynes in good yields and with excellent stereoselectivities. Experimental results showed high catalytic activity, and turnover frequency (TOF) up to 25000. Importantly, this transformation can be conducted in water, and is thus green and environmentally friendly.
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