睾酮(贴片)
内科学
内分泌学
雄烯二酮
雄甾酮
精子发生
生物
雄激素
二氢睾酮
热应力
睾丸
激素
类固醇
动物科学
医学
作者
R. P. Wettemann,Claude Desjardins
标识
DOI:10.1095/biolreprod20.2.235
摘要
Pituitary-testicular function was examined in yearling boars exposed to 23 ± 1°C (control) or 34.5 ± 1°C for 8 h and 31 ± 1°C for 16 h during each 24 h period (heat stressed). Plasma testosterone and immunoreactive LH concentrations were monitored throughout treatment and testes were removed after 13 weeks to quantify spermatogenesis and assess steroidogenesis by measuring the incorporation of [1-14C] acetate into selected [14C] androgens by slices of testicular tissue incubated in vitro. Plasma testosterone and LH concentrations were similar when control and heat stressed boars were bled infrequently during treatment. However, heat stress significantly altered androgen biosynthesis in vitro as evidenced by decreased amounts of [14C] associated with androstenedione, testosterone and dihydrotestosterone and increases in androsterone and androstanediol. Addition of LH and FSH to testicular incubates markedly enhanced the amount of [1-14C] acetate incorporated into [14C] androgens but further differences between control and heat stressed boars were not apparent. In another experiment, plasma testosterone was quantified in the serum of boars every 30 min for 12 h on Days 0, 7 and 14 during exposure to 23 ± 1°C (control) or 34.5 ± 1°C (heat stressed). Serum testosterone was reduced (P<0.10) after 7 days of heat stress.
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