节律障碍
神经科学
小脑
步态共济失调
小脑共济失调
共济失调
神经可塑性
脑刺激
运动障碍
意向性震颤
心理学
医学
刺激
病理
疾病
作者
Chiara Di Nuzzo,Fabiana Ruggiero,Francesca Cortese,Ilaria Cova,Alberto Priori,Roberta Ferrucci
出处
期刊:Cns & Neurological Disorders-drug Targets
[Bentham Science]
日期:2018-06-19
卷期号:17 (3): 193-198
被引量:16
标识
DOI:10.2174/1871527317666180404113444
摘要
Background & Objective: Non-invasive brain stimulation (NIBS) might be a valuable therapeutic approach for neurological diseases by modifying the cortical activity in the human brain and promoting neural plasticity. Currently, researchers are exploring the use of NIBS on the cerebellum to promote functional neural changes in cerebellar disorders. Conclusion: In the presence of cerebellar dysfunction, several movement disorders, such as kinetic tremor, ataxia of gait, limb dysmetria and oculomotor deficits, become progressively more disabling in daily life, and no pharmacological treatments currently exist. Conclusion: In the present mini-review, we report the main evidence concerning the use of NIBS in three specific cerebellar dysfunctions, cerebellar ataxias (CA), essential tremor (ET) and ataxic cerebral palsy, in which abnormalities of neuroplasticity and cortical excitability can be important pathophysiological factors.
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