纳米颗粒
生物利用度
没食子酸
化学
没食子酸表没食子酸酯
阿拉伯树胶
粒径
消化(炼金术)
傅里叶变换红外光谱
体外
化学工程
色谱法
抗氧化剂
多酚
核化学
材料科学
食品科学
纳米技术
生物化学
物理化学
工程类
生物
生物信息学
作者
Jianchang Jin,Chengzhi Liu,Huafei Tong,Yulu Sun,Min Huang,Gerui Ren,Hujun Xie
出处
期刊:Foods
[MDPI AG]
日期:2022-07-19
卷期号:11 (14): 2131-2131
被引量:11
标识
DOI:10.3390/foods11142131
摘要
Epigallocatechin gallate (EGCG) has many excellent qualities such as its antitumor, antiradiation and anti-oxidation properties, but its application is limited because its oral bioavailability is low and stability is poor. In this paper, zein and gum arabic (GA) were used as wall materials to prepare Zein-GA complex nanoparticles for encapsulating and protecting the EGCG. The particle size of Zein-GA-EGCG complex nanoparticles ranged from 128.03–221.23 nm, and the EGCG encapsulation efficiency reached a maximum of 75.23% when the mass ratio of zein to GA was 1:1. The FTIR and XRD results illustrated that the components of the Zein-GA-EGCG complex nanoparticles interacted by electrostatic, hydrogen bonding, and hydrophobic interactions. The EGCG release rate of Zein-GA-EGCG nanoparticles (16.42%) was lower than that of Zein-EGCG (25.52%) during gastric digestion, and a large amount of EGCG was released during intestinal digestion, suggesting that the Zein-GA-EGCG nanoparticles could achieve the sustained release of EGCG during in vitro digestion. Hence, using Zein-GA complexes to encapsulate EGCG effectively increased the encapsulation efficiency of EGCG and realized the purpose of sustained release during simulated gastrointestinal digestion.
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