Single-walled carbon nanotube biosensor for detection of E. coli

Single-walled carbon nanotube biosensor was developed for the detection of Escherichia coli using aptamer-functionalized carbon nanotube field effect transistors. RNA-based E. coli aptamer was chosen by the SELEX process, and immobilized on sidewalls of carbon nanotubes by CDI-Tween 20 linking molecules. The electrical response of the carbon nanotube sensor before and after the binding of E. coli aptamer and E. coli were studied.