Substrate and catalytic promiscuity of secondary metabolite enzymes: O -prenylation of hydroxyxanthones with different prenyl donors by a bisindolyl benzoquinone C - and N -prenyltransferase

Supplied with unnatural substrates like hydroxyxanthones, the C - and N -prenyltransferase AstPT performs O -prenylation using DMAPP, GPP and also FPP as prenyl donor.