青蒿素
医学
宫颈癌
限制
临床试验
肿瘤科
癌症
临床疗效
内科学
免疫学
疟疾
机械工程
工程类
恶性疟原虫
作者
Sarah Goodrich,Christina Schlegel,Guixang Wang,Jerome L. Belinson
出处
期刊:Future Oncology
[Future Medicine]
日期:2014-03-01
卷期号:10 (4): 647-654
被引量:14
摘要
ABSTRACT: Cervical cancer and HPV-related diseases remain a burden in the developing world. While much progress has been gained in the detection of HPV and preneoplastic cervical lesions, the rate-limiting step in the prevention of cervical cancer is management of these women. A natural compound, artemisinin, and its derivatives appear to hold promise as a simple means of treatment. Laboratory studies have shown that this compound, and its derivatives, have activity against HPV-infected and -transformed cells and cervical cancer cells. In situations of compassionate use, studies have also demonstrated efficacy in clinical situations. Well-designed clinical trials relating to its use should be undertaken.
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