Objective To explore the change on corneal topography and association with loss of spectacle-corrected visual acuity after laser in situ keratomileusis(LASIK).Methods Forty cases (80 eyes) were analysised 1,3 months by using corneal topographic analytical system postoperatively.Results The number of homogeneous pattern were the most post operation of LASIK.The main factors of loss the best correct visual acuity are the aberrent form of corneal topography and decent ration.Conclusions After LASIK ablation pattern was regular effective and stable.But the laser ablation decent ration must be paid more attention.