类有机物
生物
再生医学
胚胎干细胞
神经科学
药物开发
细胞生物学
个性化医疗
干细胞
计算生物学
生物信息学
基因
药品
遗传学
药理学
出处
期刊:Cell
[Elsevier]
日期:2016-06-01
卷期号:165 (7): 1586-1597
被引量:2053
标识
DOI:10.1016/j.cell.2016.05.082
摘要
Recent advances in 3D culture technology allow embryonic and adult mammalian stem cells to exhibit their remarkable self-organizing properties, and the resulting organoids reflect key structural and functional properties of organs such as kidney, lung, gut, brain and retina. Organoid technology can therefore be used to model human organ development and various human pathologies ‘in a dish." Additionally, patient-derived organoids hold promise to predict drug response in a personalized fashion. Organoids open up new avenues for regenerative medicine and, in combination with editing technology, for gene therapy. The many potential applications of this technology are only beginning to be explored.
科研通智能强力驱动
Strongly Powered by AbleSci AI