X-ray Value in Diagnosis of Osteogenesis Imperfecta of Fetus

Objective To evaluate the diagnostic value of X-ray in osteogenesis imperfecta of fetus. Materials and Methods X-ray findings of 6 dead fetus with osteogenesis imperfecta were analyzed retrospectively. Results Four cases with the type Ⅱ osteogenesis imperfecta were characterized by severe shortened and widened long bones and ribs, narrow thorax. Two cases with the type ⅡI osteogenesis imperfecta were characterized by multiple fractures with low bone density and thin cortical bone. X-ray findings of 6 cases were corresponded with findings in autopsy. One fetus' mother was a patient with the type I osteogenesis imperfecta. Conclusion X-ray image is critical to diagnose different types of osteogenesis imperfecta of fetus and provid important evidences for clinic diagnosis,inherited consultation and genic Diagnosis.