高甘油三酯血症
医学
内科学
作用机理
心脏病学
过氧化物酶体增殖物激活受体
临床试验
药理学
受体
胆固醇
甘油三酯
生物化学
化学
体外
作者
Fruchart Jc,Brewer Hb,Eran Leitersdorf
标识
DOI:10.1016/s0002-9149(98)00010-1
摘要
The hypolipidemic action of fibrates has recently been shown to involve the activation of peroxisome proliferator activated receptors establishing a molecular mechanism for this class of drugs. Increasing clinical trial evidence supports the efficacy of fibrates in the treatment of dyslipoproteinemias, particularly in patients with hypertriglyceridemia and low high-density lipoproteins.
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