Objective:To compare the value of ultrasonography and mammography in the diagnosis of breast cancer.Method:The retrospective study included the features of preoperative ultrasonography and mammography of breast cancer cases which was comfirmed by surgery and pathology,and compared their detection rate and the accuracy rate.Result:The accurate rate of ultrasonography and mammography was 91.84% and 85.71%,respectively,and the detection rate was 100% and 89.80%,respectively,the accurate rate of ultrasonography combined with mammography was 97.96%.Conclusion:Combined ulatrasonography and mammography could increase the detection rate and the diagnostic accuracy of breast cancer.