Tobacco bacterial wilt is a kind of bacterial disease,which is produced by Ralstonia solanacearum.It is a main disease in tropic and semi-tropical.It is introduced pathogenic bacteria of tobacco bacterial wilt,hostrange,symptoms,infestation,occurrence conditions,regularty of epidemic and nosogenesis.It was reviewed that the occurance and damage of tobacco bacterial wilt in Yunnan Province,prevention and cure method of tobacco bacterial wilt,and its prospect.