Medication Reliated Osteonecrosis of The Jaws (MRONJ); Caused by maxillofacial surgical procedures performed during or after antiresorptive, antiangiogenic and bisphosphonate treatments; It is a newly defined disease and its etiopathogenesis is still not fully understood. Studies on the definition, staging and treatment approaches of the disease are evaluated by the commission formed by the American Association of Maxillofacial Surgeons, and guidelines expressing opinions on these issues are published; Discussions still continue on the treatment approaches of the disease. Conservative, surgical, alternative and their combinations methods are used in the treatment of the disease, depending on the level of bone and soft tissues affected.