Incremental Value of Synthetic MRI Radiomics in Predicting Neoadjuvant Response in Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer

Synthetic MRI radiomics accurately predicted pathologic complete response to neoadjuvant therapy in human epidermal growth factor receptor 2–positive breast cancer, outperformed traditional radiomics models, and was associated with immune-related pathways and recurrence-free survival.