A general strategy for high-efficiency live bacteria imaging and targeted phototherapy

(MRSA)-infected skin wounds, FluoEosinY-mediated antimicrobial photodynamic therapy not only achieved marked reductions in bacterial burden but also accelerated wound healing, with negligible toxicity to host tissues. This versatile design strategy advances both the mechanistic investigation of bacterial cell wall physiology and the development of precision-targeted therapeutics to combat antibiotic-resistant infections.