Application of deep eutectic solvents in chromatography: A review

In recent years, the application of deep eutectic solvents (DESs) in chromatography has drawn considerable attention, and many interesting works have been proposed. This review summarizes the application of DESs in various aspects of the chromatographic technique, including stationary phase, mobile phase, and the preparation procedure of the chromatographic material. We focus mainly on the discussion of chromatographic performance improvements resulting from the introduction of DESs and their possible mechanisms inferred from the experimental results. This review is expected to be a guidance for the further development of chromatographic application of DESs.