Multifunctional Tubular Organic Cage‐Supported Ultrafine Palladium Nanoparticles for Sequential Catalysis

The imine condensation reaction of 5,5'-(benzo[c][1,2,5]thiadiazole-4,7-diyl)diisophthalaldehyde with cyclohexanediamine resulted in a shape-persistent multifunctional tubular organic cage (MTC1). It exhibits selective fluorescence sensing towards divalent Pd ions with a very low detection limit (38 ppb), suggesting effective complexation between these two species. Subsequent reduction of MTC1 and Pd(OAc)2 with NaBH4 afforded a cage-supported catalyst with well-dispersed ultrafine Pd nanoparticles (NPs) in a narrow size distribution (1.9±0.4 nm), denoted as Pd@MTC1-1/5. Such ultrafine Pd NPs in Pd@MTC1-1/5, in cooperation with photocatalytically active MTC1, enable efficient sequential reactions involving visible light-induced aerobic hydroxylation of 4-nitrophenylboronic acid to 4-nitrophenol and the following hydride reduction with NaBH4 . This is the first example of a multifunctional organic cage capable of sensing, directing nanoparticle growth, and catalyzing sequential reactions.