Prostacyclin : new perspectives for basic research and novel therapeutic indications : proceedings of the Symposium on Novel Perspectives in Prostacyclin Research, Vienna, Austria, 25th September 1991

Part I: New perspectives in basic research . Novel perspectives in prostacyclin research (G.M. Rubanyi). Molecular biology of prostacyclin biosynthesis (K.K. Wu et al.). Prostacyclin and platelets: A novel signal transduction mechanism (M. Torti, E.G. Lapetina). Prostacyclin and monocytes: Suppression of tissue factor activity procoagulant (D.J. Crutchley). Modulation of polymorphonuclear leukocyte function by prostaglandins and nitric oxide (R.J. Gryglewski, D. Salvemini). Interactions between endothelium-derived prostacyclin and nitric oxide: Molecular mechanisms and cellular effects (M. Hecker, R. Busse). Interaction of prostacyclin and endothelin (C. Thiemermann). Prostacyclin and vascular remodelling (H. Graf). Part II: Novel therapeutic indications . Novel therapeutic targets for prostacyclin analogues (J.R. Vane, R.M. Botting). Cytoprotective properties of Prostacyclin (K. Schror). Prostacyclin and atherosclerosis (M. Fredrich, B. Muller). Prostacyclin, hydroxy fatty acids and cancer metastasis (K.V. Honn, Y.Q. Chen). Prostacyclin in diabetes: Metabolism and therapeutic use (P. Rosen, D. Tschope). The potential use of prostacyclin in congestive heart failure (W.A. Long et al.). Antimetastatic properties of the stable prostacyclin analogue cicaprost (M. Schirner, M.R. Schneider). Author index.