化学
磺酰
铱
催化作用
组合化学
基质(水族馆)
范围(计算机科学)
反应机理
有机化学
计算机科学
海洋学
地质学
程序设计语言
烷基
作者
Hongcen Hou,Yongli Zhao,Shou‐Ri Sheng,Junmin Chen
标识
DOI:10.1002/adsc.201900573
摘要
Abstract We developed herein an iridium‐catalyzed direct C−H activation/ C−N bond formation reaction of benzenesulfonamides with sulfonyl azides. The amidation reaction provides a protocol for the synthesis of 2‐aminobenzesulfonamides in good to excellent yields. This strategy features a wide substrate scope, tolerates a broad range of functional groups under external oxidant‐free conditions and only releases molecular nitrogen as the sole by‐product. Moreover, the preliminary mechanism was investigated and the proposed reaction pathway was provided. magnified image
科研通智能强力驱动
Strongly Powered by AbleSci AI