Features of reaction between fluorine-containing glycidyl ethers and alcohols in basic medium

The reaction of fluorine-containing glycidyl ethers with various alcohols (i-PrOH, MeOH, PhOH, 2,2,3,3-tetrafluoropropanol) in basic medium resulted in products of regioselective opening of the oxirane ring. In reaction of 2,2,3,3-tetrafluoropropyloxymethyloxirane with 2-propanol under conditions of phase-transfer catalysis the main product was the corresponding 1,2-diol (yield 42%).