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Double Blinded, Randomized and Controlled Comparative Study Evaluating the Cleaning Activity of Two Ear Cleaners in Client-Owned Dogs with Spontaneous Otitis Externa

医学 中耳炎 红斑 耳道 清洁剂 牙科 随机对照试验 细胞学 听力学 外科 病理 放射科
作者
Geneviève Marignac,Jean Yanique Petit,Jean François Jamet,Loïc Desquilbet,Jean Petit,Frédérique Woehrlé,Tessa Trouchon,Oscar Fantini,Sébastien Perrot
出处
期刊:Open Journal of Veterinary Medicine [Scientific Research Publishing, Inc.]
卷期号:09 (06): 67-78 被引量:6
标识
DOI:10.4236/ojvm.2019.96006
摘要

Ear cleaning is a therapeutic component in the management of otitis externa in dogs. The objectives of this study were to evaluate the in vivo efficacy and safety of a new ear cleanser, Sonotix® against EpiOtic® Advanced for the management of canine otitis externa. Eighteen clients owned dogs with a diagnosis of erythemato-ceruminous or purulent otitis externa were prospectively included and randomized to two treatment group: EpiOtic® Advanced and Sonotix®. Cytology and video-otoscopic examination (erythema, amount of cerumen and thickness and surface of ear canal covered by cerumen) of all affected ears were done at D0, both before (T0) and 30 minutes (T0 + 30 min) after ear cleaning. Then an ear medication was applied (Aurizon®, Vetoquinol). Owners were instructed to clean affected ears daily and apply the ear medication 30 minutes later for 5 days (D1-D5). Dogs were seen again at D6 for cytology and video-otoscopic examination. At T0, no significant differences were found between both ear cleansers groups regarding macroscopic and microscopic scorings. At T0 + 30 min and D6 cytological and video-otoscopic scores were significantly decreased (Wilcoxon test; p ® was statistically superior to Epiotic® as evidenced by the median global scores of video-otoscopic examination at T0 + 30 min (Mann Whitney Test, p ® seems to be more effective in removing cerumen than EpiOtic® Advanced.
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