医学
眼科
脉络膜新生血管
纤维化
新生血管
视网膜
病理
光学相干层析成像
内科学
血管生成
作者
Ugo Introini,Giuseppe Casalino,Kamron Khan,Chiara M Eandi,Camilla Alovisi,Michel Michaelides,Francesco Bandello
出处
期刊:Ophthalmic surgery, lasers & imaging retina
日期:2018-11-01
卷期号:49 (11): 888-892
被引量:7
标识
DOI:10.3928/23258160-20181101-10
摘要
The authors report the clinical course of two cases of autosomal recessive bestrophinopathy (ARB) complicated by choroidal neovascularization (CNV). One patient presenting with a novel BEST1 mutation (c.658 C>T, p.Gln220*) underwent anti-vascular endothelial growth factor therapy. Response to treatment was documented on optical coherence tomography angiography (OCTA). Despite initial response to treatment, recurrent CNV exudation with progressive subretinal fibrosis was observed. In the second patient, the CNV was not treated and spontaneous regression was observed. This report indicates that the clinical course of CNV in ARB may vary considerably, ranging from spontaneous regression to progressive subretinal fibrosis despite intervention. [ Ophthalmic Surg Lasers Imaging Retina. 2018;49:888–892.]
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