咪唑吡啶
安全概况
化学
二酰甘油激酶
生物化学
药理学
生物
立体化学
酶
不利影响
蛋白激酶C
作者
Kentaro Futatsugi,Kim Huard,Daniel W. Kung,John C. Pettersen,Declan Flynn,J Gosset,Gary E. Aspnes,Robert J. Barnes,Shawn Cabral,Matthew Dowling,Dilinie P. Fernando,Theunis C. Goosen,William Gorczyca,David Hepworth,Michael Herr,Sophie Y. Lavergne,Q. Li,Mark Niosi,Suvi T. M. Orr,Ingrid D. Pardo
出处
期刊:MedChemComm
[Royal Society of Chemistry]
日期:2016-11-22
卷期号:8 (4): 771-779
被引量:8
摘要
Preclinical pharmacokinetic, efficacy, and toxicology results are reported for a series of DGAT2 inhibitors for the potential treatment of hypertriglyceridemia.
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