Is Severe Traumatic Brain Injury no Longer a Contra-Indication for Surgical Stabilization of Rib Fractures in Patients with Multiple Rib Fractures? A Propensity-Matched Analysis

医学 倾向得分匹配 禁忌症 创伤性脑损伤 重症监护室 子群分析 回顾性队列研究 外科 内科学 置信区间 替代医学 病理 精神科
作者
Emanuele Lagazzi,Amory de Roulet,Jefferson A. Proaño-Zamudio,Dias Argandykov,Anne-Sophie C. Romijn,May Abiad,Wardah Rafaqat,John O. Hwabejire,George C. Velmahos,Charudutt Paranjape
出处
期刊:The journal of trauma and acute care surgery [Lippincott Williams & Wilkins]
卷期号:94 (6): 823-830 被引量:2
标识
DOI:10.1097/ta.0000000000003954
摘要

Traumatic brain injury (TBI) is often considered a contraindication to surgical stabilization of rib fractures (SSRF). In this study, we hypothesized that, compared with nonoperative management, SSRF is associated with improved outcomes in TBI patients.Using the American College of Surgeons Trauma Quality Improvement Program 2016-2019, we performed a retrospective analysis of patients with concurrent TBI and multiple rib fractures. Following propensity score matching, we compared patients who underwent SSRF with those who were managed nonoperatively. Our primary outcome was mortality. Secondary outcomes included ventilator-associated pneumonia, hospital and intensive care unit (ICU) length of stay (LOS), ventilator days, tracheostomy rate, and hospital discharge disposition. In a subgroup analysis, we stratified patients into mild and moderate TBI (GCS score >8) and severe TBI (GCS score ≤8).Of 36,088 patients included in this study, 879 (2.4%) underwent SSRF. After propensity-score matching, compared with nonoperative management, SSRF was associated with decreased mortality (5.4% vs. 14.5%, p < 0.001), increased hospital LOS (15 days vs. 9 days, p < 0.001), increased ICU LOS (12 days vs. 8 days, p < 0.001), and increased ventilator days (7 days vs. 4 days, p < 0.001). In the subgroup analyses, in mild and moderate TBI, SSRF was associated with decreased in-hospital mortality (5.0% vs. 9.9%, p = 0.006), increased hospital LOS (13 days vs. 9 days, p < 0.001), ICU LOS (10 days vs. 7 days, p < 0.001), and ventilator days (5 days vs. 2 days, p < 0.001). In patients with severe TBI, SSRF was associated with decreased mortality (6.2% vs. 18%, p < 0.001), increased hospital LOS (20 days vs. 14 days, p = 0.001), and increased ICU LOS (16 days vs. 13 days, p = 0.004).In patients with TBI and multiple rib fractures, SSRF is associated with a significant decrease in in-hospital mortality and with longer hospital and ICU LOSs. These findings suggest that SSRF should be considered in patients with TBI and multiple rib fractures.Therapeutic/Care Management; Level III.

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