High‐performance non‐enzymatic glucose sensor based on Co 3 O 4 /rGO nanohybrid

Abstract There has been substantial interest in designing and fabricating electrochemical non‐enzyme sensors for glucose detection with a focus on the nanocomposites used between metal oxide and the two‐dimensional material. In this work, Co 3 O 4 /reduced graphene oxide (rGO) nanocomposite was obtained and used as a modified electrochemical electrode for the detection of trace glucose. According to the results, the electrocatalytic performances of Co 3 O 4 nanoparticles for the oxidation of glucose were substantially enhanced with the addition of a small amount of rGO. Specifically, the Co 3 O 4 /rGO modified electrode exhibited a sensitivity of 82 μA·mmol −1 ·cm −2 , a detection limit of 50 μmol·L −1 (signal noise ratio ( S / N ) = 3), and a fast response time of about 1 s under optimal conditions. The enhanced performances of the Co 3 O 4 /rGO modified electrode are attributable to the high absorption oxygen (O Ads ) and synergistic effect between Co 3 O 4 and rGO. The results indicate that Co 3 O 4 /rGO nanocomposite is a promising candidate for being used as the active material in real‐world electrochemical biosensors.