成牙本质细胞
成釉细胞
解剖
搪瓷漆
牙瘤
牙髓(牙)
下颌骨(节肢动物口器)
生物
病理
医学
牙科
牙源性的
动物
属
作者
Keith Lewy,Mayane Faccin,Yogish Somayaji,Kamryn Pursell,Brian F. Porter,Tracy H Vemulapalli,Jonathan Bova
标识
DOI:10.1016/j.jcpa.2022.11.003
摘要
Reports of compound odontomas in rats are very rare. A 14-month-old adult male Sprague Dawley rat was found to have a hard mass associated with the caudal aspect of the left mandible. After 2 weeks of observation, the rat was euthanized due to the mass growing significantly in size and the rat losing >20% of its body weight. Grossly, the mass was well-circumscribed, 3.7 × 3 × 1.2 cm, hard and heterogeneously coloured white, tan and red. The mass was restricted to the mandibular bone and did not involve surrounding subcutaneous tissue. On cut surface, the mass was a similar colour and brittle. Histologically, there were numerous proto-teeth embedded in ossified stroma. Each proto-tooth had a central mesenchyme pulp surrounded by columnar odontoblasts and dentine matrix. The dentine was often bordered by enamel matrix, which was occasionally bounded by ameloblasts. These histological findings were consistent with a compound odontoma. This is the first report of a spontaneous compound odontoma in the caudal mandible of a rat.
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