Basic Formulation Semblance and Contemporary Approach of Mini Tablets

灵活性(工程) 剂型 颗粒 涂层 材料科学 生物医学工程 赋形剂 多药 明胶 计算机科学 医学 纳米技术 数学 药理学 复合材料 化学 统计 生物化学
作者
Deepak Kumar Sarangi,Chandra Sekhar Patro,Chinam Niranjan Patra,Gurudutta Pattnaik,Jnyanranjan Panda
出处
期刊:International journal of pharmaceutical sciences and nanotechnology [BSP Books Private Limited]
卷期号:16 (1): 6325-6336 被引量:1
标识
DOI:10.37285/ijpsn.2023.16.1.6
摘要

As a new approach to solid dosage forms, mini-tablets (MTs) are designed to subjugate some kind of therapeutic disincentives, like poor swallowing properties and polypharmacy therapy, as well as to provide therapeutic advantages like dose flexibility and release patterns. These pills are a viable method of delivering medication to patients. It has smaller tablets than typical, with a diameter of between 2 and 3 mm, compared to conventional tablets. Other advantages of tiny tablets include their uniform shape and size, which reduces unit-to-unit fluctuation in the medicine and allows for precise weighing of the substance. Since they have a very smooth surface area, it is possible to cover them with a drug-delaying coating in order to prolong their shelf life. It can also be used in the same way as other multiple-dose forms, such as capsules. MTs are a good substitute for pellets and granules. Lower potential drugs can be encapsulated as mini tablets in different sizes of gelatin capsule shells if the qualities are adequately regulated. This review article depicts various aspects of mini-tablets, such as their marketed product, types, formulation prospects, current trends of manufacturing, novelties in research work, and patent-related works that will be beneficial for those who are conducting research on the formulation and development of this mini tablet dosage form.

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