Sensitive detection of Golgi protein 73 by magnetic separation combined with a dual nanozyme MOF-818 and magnetic nucleus@bifunctional shell (Fe3O4@PB-Au) cascade reaction catalytic amplification strategy

. The proposed colorimetric biosensor was successfully applied to the determination of GP73 in spiked human serum samples with recoveries of 96.15-100.95% and RSDs of 1.52-6.85%, which demonstrated the great potential of the highly sensitive GP73 assay in clinical detection.