Department of Research & Development, Chiesi Farmaceutici, Parma, Italy i+HeALTH Strategic Research Group, Department of Health Sciences, Miguel de Cervantes European University (UEMC), Valladolid, Spain Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy School of Pharmacy, University of Rome "Tor Vergata", Rome, Italy Laboratory of Pharmacology of Synaptic Plasticity, EBRI Rita Levi-Montalcini Foundation, Rome, Italy *Correspondence to: Bruno P. Imbimbo, PhD, [email protected]. This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 4.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.