Electrochemically Promoted Skeleton Transformation of 2,1‐Benzisoxazoles to Alkyl Sulfones

Abstract This study developed an electrochemically promoted skeleton transformation reaction of 2,1‐benzisoxazoles to synthesize alkyl sulfones. Alkyl sulfones were synthesized in 68–93% yield by using 2,1‐benzisoxazole and sulfonate as substrates, and acetonitrile and water as solvents. Mechanism studies showed that this reaction involves ring opening, removal of the oxygen atom of the 2,1‐benzisoxazoles, and C( sp 3 )‐sulfonylation under electrochemical conditions.