牙髓炎
医学
牙髓(牙)
重症监护医学
牙科
动物模型
疾病
根管
牙齿骨折
牙髓切断术
临床治疗
牙髓切除术
牙髓治疗
作者
Ke Xu,Li‐Jun Huo,She Rui,X Y Li,Jialing Wu
出处
期刊:PubMed
[National Institutes of Health]
日期:2025-11-09
卷期号:60 (11): 1292-1299
标识
DOI:10.3760/cma.j.cn112144-20250714-00264
摘要
Pulpitis is a prevalent inflammatory disease in dentistry, and root canal therapy remains the primary clinical treatment for it. However, pulp removal leads to reduced tooth fracture resistance and complications such as secondary infection and tooth fracture. As a potential alternative, vital pulp therapy (VPT) relies on precise assessment of pulp status; yet current clinical diagnostic methods lack specificity. The establishment of appropriate animal models for pulpitis is crucial for investigating its pathogenesis, developing specific diagnostic biomarkers, and optimizing VPT strategies. This review systematically summarizes experimental animals selection based on anatomical compatibility and pathological similarity, as well as model construction methods and multimodal evaluation systems for pulpitis animal models, aiming to provide insights for related researches.
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