The aim of this work is the longterm study of life quality of 25 patients with bronchial asthma in the clinical remission phase depending on the infection of Clamydophila pneumoniae and Mycoplasma pneumoniae and in 125 practically healthy persons correlated by sex and age. Changes of life quality of patients were deduced by the complex estimation of the special (AQLQ) and general (SF-36) questionnaires. The unfavourable effect of latent infection of Chlamydophila pneumoniae and Mycoplasma pneumoniae on life quality of patients with bronchial asthma in the clinical remission phase is revealed. The studies on the improvement of the diagnosis of Chlamydophila and Mycoplasma infection in bronchial asthma with the following development of antibacterial eradication problems and the subsequent estimation of correlated changes of life quality of patients should be seen as highly promising.