新生
胰腺
β细胞
祖细胞
再生医学
干细胞
PAX4型
生物
导管细胞
细胞谱系
细胞生物学
癌症研究
内科学
作者
Huan Zhao,Kathy O. Lui,Bin Zhou
标识
DOI:10.1016/j.cmet.2021.10.007
摘要
Finding endogenous, renewable sources for insulin-producing beta cells in the adult pancreas is one of the holy grails of stem cell research and regenerative medicine. Through lineage tracing and scRNA-seq approaches, Gribben et al. (2021) have recently reported that Ngn3-expressing ductal cells could serve as progenitors for new beta cells in the adult pancreas.
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