多细胞生物
生物
合成生物学
统一
模块化设计
生化工程
系统生物学
计算生物学
计算机科学
细胞
工程类
遗传学
操作系统
程序设计语言
作者
Nicolas E. Grandel,Kiara Reyes Gamas,Matthew R. Bennett
标识
DOI:10.1016/j.tim.2021.04.001
摘要
While synthetic microbial systems are becoming increasingly complicated, single-strain systems cannot match the complexity of their multicellular counterparts. Such complexity, however, is much more difficult to control. Recent advances have increased our ability to control temporal, spatial, and community compositional organization, including modular adhesive systems, strain growth relationships, and asymmetric cell division. While these systems generally work independently, combining them into unified systems has proven difficult. Once such unification is proven successful we will unlock a new frontier of synthetic biology and open the door to the creation of synthetic biological systems with true multicellularity.
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