自身抗体
医学
发病机制
胆汁淤积
免疫学
胃肠病学
内科学
抗体
作者
Yao-hong Shi,Z J Zhang,Lei Shen
出处
期刊:PubMed
[National Institutes of Health]
日期:2021-02-20
卷期号:29 (2): 175-178
标识
DOI:10.3760/cma.j.cn501113-20190323-00093
摘要
Primary biliary cholangitis (PBC) is a chronic, progressive, intrahepatic cholestasis disease. Its occurrence and development are accompanied by changes in the titer of autoantibodies. However, its pathogenesis, extent of autoantibody changes and their effects are not yet fully understood. Therefore, there is a lack of effective methods for early diagnosis of PBC in patients. Finding specific PBC autoantibody markers will greatly improve the diagnostic efficiency and save early treatment time, thereby improving therapeutic effect and prognosis. This article summarizes several PBC-related serum autoantibody markers.
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