This paper compares the economic performance of holiday and residential tourism destinations in Spain, as measured by the level of retail activity, from a quantitative perspective. Differences between destinations are explored. A positive association between the economic development of destinations and their retail index was expected. However, no significant differences were found between residential/second-home tourism and holiday/leisure tourism destinations. The results obtained contradict the conventional assumptions that holiday destinations perform better economically than residential ones due to a higher level of tourist spending of people accommodated in hotels.