作者
Steven Brem,Philip J. Bierman,Henry Brem,Nicholas Butowski,Marc C. Chamberlain,E. Antonio Chiocca,Lisa M. DeAngelis,Robert A. Fenstermaker,Allan H. Friedman,Mark R. Gilbert,Deneen Hesser,Larry Junck,Gerald P. Linette,Jay S. Loeffler,Moshe Maor,Madison Michael,Paul L. Moots,Paul L. Moots,Maciej M. Mrugała,Burt Nabors,Herbert B. Newton,Jana Portnow,Jeffrey J. Raizer,Lawrence D. Recht,Dennis C. Shrieve,Allen K. Sills,Frank D. Vrionis,Patrick Y. Wen
摘要
In 2010, an estimated 22,020 new cases of primary brain and other nervous system neoplasms were diagnosed in the United States, 1 and approximately 13,140 deaths occurred from these tumors.The incidence of primary malignant brain tumors has been increasing over the past 30 years, especially in elderly persons. 2 Metastatic disease to the central nervous system (CNS) occurs much more frequently, with an estimated incidence approximately 10 times that of primary brain tumors.Between 20% and 40% of patients with systemic cancer will develop brain metastases.