微生物群
神经炎症
肠道菌群
免疫学
生物
疾病
医学
发病机制
小胶质细胞
认知功能衰退
肠-脑轴
炎症
痴呆
失调
病理
生物信息学
作者
Chun Chen,Jianming Liao,Yiyuan Xia,Xia Liu,Rheinallt M. Jones,John P. Haran,Beth A. McCormick,Timothy R. Sampson,Ashfaqul Alam,Keqiang Ye
出处
期刊:Gut
[BMJ]
日期:2022-01-11
卷期号:71 (11): 2233-2252
被引量:432
标识
DOI:10.1136/gutjnl-2021-326269
摘要
These findings support that a complex gut microbiome is required for behavioural defects, microglia activation and AD pathologies, the gut microbiome contributes to pathologies in an AD mouse model and that dysbiosis of the human microbiome might be a risk factor for AD.
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