Cerebral venous sinus thrombosis in nephrotic syndrome

A 36-year-old woman presented to the emergency department with recurrent syncope. She was diagnosed with nephrotic syndrome 16 days previously. Since she refused a kidney biopsy, she had been empirically treated with oral prednisone. A noncontrast computed tomography scan of the brain showed a high-density shadow in the superior sagittal sinus (Supplementary Figure S1A) and right transverse sinus (Supplementary Figure S1B), suggesting thrombosis. The patient was started on s.c. enoxaparin immediately.