Adipose-derived stem cell exosomes promote neurological recovery after subarachnoid hemorrhage via AMPK/mTOR-mediated TFEB activation

Background Subarachnoid hemorrhage (SAH) is a common neurologically devastating disorder, and existing treatment options remain very limited. Increasing evidence has confirmed the neuroprotective effects of exosomes derived from mesenchymal stem cells (MSC). Our work investigates that adipose-derived stem cell exosomes (ADSC-Exos) exert therapeutic effects against SAH through autophagy-related pathways.