透皮
纳米技术
控制释放
医学
材料科学
生物医学工程
药理学
作者
Parbeen Singh,Brian Youden,Andrew Carrier,Ken D. Oakes,Mark R. Servos,Runqing Jiang,Lei Qin,Thanh D. Nguyen,Xu Zhang
标识
DOI:10.1016/j.jconrel.2022.12.036
摘要
Microneedles (MN) technology is an emerging technology for the transdermal delivery of therapeutics. When combined with photoresponsive (PR) materials, MNs can deliver therapeutics precisely and effectively with enhanced efficacy or synergistic effects. This review systematically summarizes the therapeutic applications of PRMNs in cancer therapy, wound healing, diabetes treatment, and diagnostics. Different PR approaches to activate and control the release of therapeutic agents from MNs are also discussed. Overall, PRMNs are a powerful tool for stimuli-responsive controlled-release therapeutic delivery to treat various diseases.
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