医学
胶质瘤
神经外科
切除术
胶质母细胞瘤
神经学
替莫唑胺
重症监护医学
医学物理学
外科
精神科
癌症研究
作者
Andrew A. Hardigan,Joshua D. Jackson,Anoop P. Patel
出处
期刊:Seminars in Neurology
[Georg Thieme Verlag KG]
日期:2023-11-14
卷期号:43 (06): 810-824
标识
DOI:10.1055/s-0043-1776766
摘要
Abstract The care of patients with both high-grade glioma and low-grade glioma necessitates an interdisciplinary collaboration between neurosurgeons, neuro-oncologists, neurologists and other practitioners. In this review, we aim to detail the considerations, approaches and advances in the neurosurgical care of gliomas. We describe the impact of extent-of-resection in high-grade and low-grade glioma, with particular focus on primary and recurrent glioblastoma. We address advances in surgical methods and adjunct technologies such as intraoperative imaging and fluorescence guided surgery that maximize extent-of-resection while minimizing the potential for iatrogenic neurological deficits. Finally, we review surgically-mediated therapies other than resection and discuss the role of neurosurgery in emerging paradigm-shifts in inter-disciplinary glioma management such as serial tissue sampling and “window of opportunity trials”.
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