Nickel oxide nanoparticles modified with dimethylglyoxime grafted on a cellulose surface as an efficient adsorbent for thin film microextraction of tramadol in biological fluids followed by its determination using HPLC

In the current study, nickel oxide nanoparticles (NiO NPs) modified with dimethylglyoxime (DMG) were deposited onto the cellulose surface (Ni(DMG) 2 -NiO-Cell) and used as an efficient adsorbent for thin film microextraction (TFME) of tramadol (TRA).