芳基
分子内力
化学
电泳剂
环加成
亲核细胞
叶立德
Atom(片上系统)
药物化学
计算化学
立体化学
有机化学
催化作用
计算机科学
嵌入式系统
作者
Tsukasa Tawatari,Ritsuki Kato,Riku Kudo,Kiyosei Takasu,Hiroshi Takikawa
标识
DOI:10.1002/anie.202300907
摘要
We report herein intramolecular (3+2) cycloaddition reactions between ynamides as three-atom components and benzyne. In these intramolecular reactions, the two-bond formation is realized by exploiting benzyne precursors that contain a chlorosilyl group as a linking functionality. This method thus highlights the ambivalent character of the intermediate indolium ylide, which exhibits both nucleophilic and electrophilic properties at its C2 atom.
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