医学
蛋白尿
肾脏疾病
内科学
2型糖尿病
糖尿病
疾病
内分泌学
作者
Rajiv Agarwal,Wanzhu Tu,Alfredo E. Farjat,Youssef M.K. Farag,Robert D. Toto,Sanjay Kaul,Robert Lawatscheck,Katja Rohwedder,Luís M. Ruilope,Peter Rossing,Bertram Pitt,Gerasimos Filippatos,Stefan D. Anker,George L. Bakris,Augusto Vallejos,Richard J. MacIsaac,Guntram Schernthaner,Pieter Gillard,Maria Eugênia Fernandes Canziani,Theodora Temelkova‐Kurktschiev
摘要
In patients with chronic kidney disease (CKD) and type 2 diabetes (T2D), finerenone, a nonsteroidal mineralocorticoid receptor antagonist, reduces cardiovascular and kidney failure outcomes. Finerenone also lowers the urine albumin-to-creatinine ratio (UACR). Whether finerenone-induced change in UACR mediates cardiovascular and kidney failure outcomes is unknown.
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