医学
子宫内膜异位症
生活质量(医疗保健)
泌尿系统
随机对照试验
尿失禁
泌尿科
前瞻性队列研究
腹腔镜检查
外科
内科学
护理部
作者
Kimberly H. Nguyen,Lalla McCormack,Rebecca Deans,Erin Nesbitt‐Hawes,Blake Knapman,Fiona Li,Claire Yinn Lim,Jason Abbott
标识
DOI:10.1016/j.jmig.2023.11.020
摘要
ABSTRACT
Study Objective
To assess long-term urinary function for women having laparoscopic surgery for endometriosis. Design
Institutional Review Board-approved nested cohort study within a larger randomized controlled trial assessing urinary function following any benign laparoscopy for gynecological presentations. Setting
Two tertiary-level university-affiliated hospitals. Patients
Women with histologically confirmed endometriosis within the randomized controlled trial between April 2012 and November 2019, where baseline urinary function was determined. Interventions
Women with histologically confirmed endometriosis were contacted between February and October 2020, and urinary function was re-assessed. Measurements and Main Results
Urinary function was assessed using validated questionnaires across the domains of filling, voiding, incontinence, and quality of life determined distant from surgery. Higher scores correlated with a greater severity of symptoms. From 518/711 (72.9%) women with histologically confirmed endometriosis, 289/518 (55.8%) consented to the nested study. At a mean of 50 months (range 12–103 months) post-operatively, 35 participants (12.1%) had sought treatment for bladder symptoms, and 81 participants (28.0%) reported at least one urinary tract infection since their index surgery. There was a significant worsening of symptoms for filling, voiding, incontinence, and quality of life pre-operative to post-operatively (2.27 vs 3.32, 0.93 vs 2.02, 1.06 vs 2.32, 0.83 vs 2.13 respectively, p <.001). There was no statistically significant difference in urinary questionnaire scores in participants with and without uterovesical endometriosis. There was no statistically significant difference in any parameter when comparing any revised American Society of Reproductive Medicine (rASM) stage of endometriosis. Participants who had post-operative urinary retention reported a higher mean voiding score than those who did not (3.24 vs 1.94, p=.017), while participants with post-operative urinary tract infection reported a higher mean frequency score than those who did not (5.17 vs 3.24, p=.016). Conclusion
This study suggests a decline in urinary function over time following laparoscopic surgery for endometriosis that is not dependent on the severity or location of the disease.
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