Clinical Significance of Early Hyperglycemia in Nondiabetic Patients with Acute Myocardial Infarction

Objective: To investigate the clinical significance of early hyperglycemia in nondiabetic patients with acute myocardial infarction (AMI). Methods: The clinical data of 258 nondiabetic patients with AMI were collected and divided into 3 groups on the basis of admission fast blood glucose (FBS) level: normal group (FBS7.0 mmol/L, n=112), higher FBS group (7.0 mmol/L≤FBS11.1 mmol/L, n=82), and highest FBS group (FBS≥11.1 mmol/L, n=64). The complications, mortality, infarction size, myocardial enzyme and cardiac function of the three groups' of patients were compared and analysed. Results: The mortality, the incidence of complication, the rate of compound myocardial infarction and the myocardial enzyme were all higher in higher FBS groups than that of normal one (P 0.01), but the cardiac function was lower in group with higher FBS than that of normal group (P 0.01). The glucose level was relevant to all above parameters. Conclusion: The phenomenon of early hyperglycemia in nondiabetic patients with AMI indicates the more serious conditions, wider area of infarction, more complications, worse prognosis and higher mortality.