化学
胺气处理
硼烷
药物化学
叔胺
有机化学
环胺
硼烷
酰胺
作者
Mark R. Ebden,Nigel S. Simpkins,David Fox
出处
期刊:Tetrahedron
[Elsevier]
日期:1998-10-01
卷期号:54 (42): 12923-12952
被引量:31
标识
DOI:10.1016/s0040-4020(98)00783-2
摘要
Formation of borane complexes of N, N-dimethylbenzylamine, N,N-dimethyl(1-naphthyl)methylamine, N,N-dimethyl(2-naphthyl)methylamine, N-methyltetrahydroisoquinoline and N-methylisoindoline facilitates regioselective metallation of these systems using BuLi, giving intermediate benzylic anions which react with a range of electrophiles to give products in good yield.
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