This preliminary study is designed to explore the multifaceted impact of Generative Artificial Intelligence (GenAI) integrated into digital learning platforms, namely AISI, on students' science learning, self-regulation, and epistemic beliefs from 129 college students. Leveraging empirical study data, Epistemic Network Analysis (ENA) was utilized to quantitatively explore relationships between students' learning preferences (high AI-centered preference group and low AI-centered preference group), their epistemic beliefs concerning AI (certainty, justification, complexity), and their self-regulated learning strategies (adaptation, planning). The findings show that students in the high AI-centered preference group tend to believe that knowledge provided by GenAI is uncertain and complex. This study aims to contribute to GenAI-enhanced learning environments and pedagogical practices that foster critical AI literacy and adaptive self-regulated learning.